Sandboxing is a technique that insulates the sandboxed objects from your real system. Should a virus attack the sandbox, it does not affect your system. When you end the sandboxed session, all traces of that session will disappear.Many people think that sandboxing is difficult to use. It is, in fact, very, very simple. Here is what you do to be safe on the web, which I think is the most important. The other functions you can explore yourself.
Step1 - Download and install Sandboxie from here: http://www.sandboxie.com/index.php?DownloadSandboxie
For 64bit go here and use the second link.
Step2 - Go into All Programs, click on Sandboxie and make a shortcut on the desktop from “Run webbrowser sandboxed” (you can also pin it to the Start menu, Quick launch or Taskbar).
Step3 - Launch your webbrowser with that shortcut. Now you are safe.